NMDA receptor-targeted enrichment of CaMKIIα improves fear memory.

Chifor A, Choi J, Park J.

iScience (2022) 25: 104864. doi:10.1016/j.isci.2022.104864 PMID: 35996578 PMCID: PMC9391594

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The Troyer syndrome protein spartin mediates selective autophagy of lipid droplets.

Chung J, Park J, Lai ZW, Lambert TJ, Richards RC, Farese RV Jr, Walther TC.

bioRxiv doi:10.1101/2021.08.18.456894

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Protein phosphatase PPM1B inhibits DYRK1A kinase through dephosphorylation of pS258 and reduces toxic tau aggregation.

Lee YH, Im E, Hyun M, Park J, Chung KC.

J Biol Chem (2021) 296: 100245. doi:10.1074/jbc.RA120.015574 PMID: 33380426 PMCID: PMC7948726

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TMEM163 regulates ATP-gated P2X receptor and behavior.

Salm EJ, Dunn PJ, Shan L, Yamasaki M, Malewicz NM, Miyazaki T, Park J, Sumioka A, Hamer RRL, He WW, Morimoto-Tomita M, LaMotte RH, Tomita S.

Cell Rep (2020) 31: 107704. doi:10.1016/j.celrep.2020.107704 PMID: 32492420 PMCID: PMC7337098

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Phosphorylation of the AMPAR-TARP Complex in Synaptic Plasticity.

Park J.
Proteomes (2018) 6: 40. Review. doi:10.3390/proteomes6040040 PMID: 30297624 PMCID: PMC6313930

• Special Issue "Neuroproteomics"

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CaMKII phosphorylation of TARPγ-8 is a mediator of LTP and learning and memory.

Park J, Chávez AE, Mineur YS, Morimoto-Tomita M, Lutzu S, Kim KS, Picciotto MR, Castillo PE, Tomita S.

Neuron (2016) 92: 75-83. doi:10.1016/j.neuron.2016.09.002 PMID: 27667007 PMCID: PMC5059846

• F1000Prime Recommended.

• Highlighted in Lewis S (2016) Synaptic plasticity: TARP target. Nat Rev Neurosci 17: 671.

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New perspectives of Dyrk1A role in neurogenesis and neuropathologic features of Down syndrome.

Park J, Chung KC.

Exp Neurobiol (2013) 22: 244-248. Review. doi:10.5607/en.2013.22.4.244 PMID: 24465139 PMCID: PMC3897685

 

Dyrk1A negatively regulates the actin cytoskeleton through threonine phosphorylation of N-WASP.

Park J, Sung JY, Park J, Song WJ, Chang S, Chung KC.

J Cell Sci (2012) 125: 67-80. doi:10.1242/jcs.086124 PMID: 22250195

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ASK1 negatively regulates the 26S proteasome.

Um JW, Im E, Park J, Oh Y, Min B, Lee HJ, Yoon JB, Chung KC.

J Biol Chem (2010) 285: 36434-36446. doi:10.1074/jbc.M110.133777 PMID: 20843792 PMCID: PMC2978573

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Dyrk1A phosphorylates p53 and inhibits proliferation of embryonic neuronal cells.

Park J, Oh Y, Yoo L, Jung MS, Song WJ, Lee SH, Seo H, Chung KC.

J Biol Chem (2010) 285: 31895-31906. doi:10.1074/jbc.M110.147520 PMID: 20696760 PMCID: PMC2951261

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Function and regulation of Dyrk1A: towards understanding Down syndrome.

Park J, Song WJ, Chung KC.

Cell Mol Life Sci (2009) 66: 3235-3240. Review. doi:10.1007/s00018-009-0123-2 PMID: 19685005

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Two key genes closely implicated with the neuropathological characteristics in Down syndrome: DYRK1A and RCAN1.

Park J, Oh Y, Chung KC.

BMB Reports (2009) 42: 6-15. Review. PMID: 19192387

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Down syndrome critical region 2 protein inhibits the transcriptional activity of peroxisome proliferator-activated receptor β in HEK293 cells.

Song HJ, Park J, Seo SR, Kim J, Paik SR, Chung KC.

Biochem Biophys Res Commun (2008) 376: 478-482. doi:10.1016/j.bbrc.2008.09.017 PMID: 18793612

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NF-κB-inducing kinase phosphorylates and blocks the degradation of Down syndrome candidate region 1.

Lee EJ, Seo SR, Um JW, Park J, Oh Y, Chung KC.

J Biol Chem (2008) 283: 3392-3400. doi:10.1074/jbc.M706707200 PMID: 18056702

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Dyrk1A overexpression in immortalized hippocampal cells produces the neuropathological features of Down syndrome.

Park J, Yang EJ, Yoon JH, Chung KC.

Mol Cell Neurosci (2007) 36: 270-279. doi:10.1016/j.mcn.2007.07.007 PMID: 17720532

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α-Synuclein overexpression reduces gap junctional intercellular communication in dopaminergic neuroblastoma cells.

Sung JY, Lee HJ, Jeong EI, Oh Y, Park J, Kang KS, Chung KC.

Neurosci Lett (2007) 416: 289-293. doi:10.1016/j.neulet.2007.02.025 PMID: 17337120